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A typical initial course might involve one 3ml ampoule administered intramuscularly once daily or 2-3 times per week for several weeks, followed by a maintenance dose if necessary, based on individual response and clinical need

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Natural compounds like midazolam, vitamin B12, metformin, Cangrelor, and hesperidin have also shown anti-inflammatory effects in preclinical MIRI models, often by modulating macrophage polarization or inhibiting inflammatory pathways like NF-B (Xu et al., 2024)

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